bulking Tamoxifen Citrate Tamoxifen CAS NO.10540-29-1
|Place of Origin:||China|
|Min.Order Quantity:||10 Metric Tons|
|Price:||USD $10 - $10 / Metric Ton|
Product name: Tamoxifen
Trade name: nolvadex
Molecular Weight: 563.65
Tamoxifen Citrate Content: 99%
Quality standard: USP31
Apperance: white to milk white crystalline powder
Packing: as your require
Storage: shading, confined preservation.
tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite,hydroxytamexifen.in other tissue such as the endometrium, tamoxifen behaves as an agonist. Hence tamoxifen maybe be characterized as a mixed agonist, tamoxifen has been the standard endocrine therapy for hormone receptor-postive early breast cancer in pre-menopausal women, although aromatase inhibitors has been proposed.
Nolvadex is the trade name for the drug tamoxifen citrate, it is a non-steroidal agent that demonstrates potent anti-estrogenic properties. The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. With the tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an anti-estrogenic effect is achieved. Since many forms of breast cancer are responsive to estrogen, the ability of tamoxifen citrate to block its action in such cells has proven to be a very effective treatment. It is also utilized successfully as a preventative measure, taken by people with an extremely high familial tendency for breast cancer. While Nolvadex is effective against estrogen, it is not our strongest available remedy. We now have the drugs Arimidex, Femara, and Aromasin available to us, which notably prevents estrogen from being manufactured in the first place. Altering the effect of estrogen in the female body can cause a level of discomfort, so anti-estrogens are most bearable when used after the point of menopause. Since Nolvadex is milder in comparison, it is more widely applicable and usually the first treatment option.